Myriad MyRisk

Information for Healthcare Providers

Myriad MyRisk is a germline test that screens for 48 genetic mutations associated with 11 hereditary cancers. This test can be very insightful for men with a family history of breast, colon, rectal, or uterine cancer under age 50; or ovarian, metastatic prostate, pancreatic cancers. It can also help men with prostate cancer determine if their cancer may be one of the 10% of cases associated with hereditary cancer and their  family members may be at greater risk for cancer. Insights help healthcare providers make a more informed decision about treatment recommendations. 

Myriad MyRisk Test Benefits

  • Provides personalized test results that can influence treatment plans 
  • Has been associated with a change in medical management to reduce cancer risk in 56% of patients
  • Only requires a saliva sample 
  • Results are available within 2 weeks 
  • Is covered by most major insurance companies 

Myriad MyRisk Physician Video 

Learn more about the Myriad MyRisk germline test.


For Healthcare Providers: How to Order the Myriad MyRisk Test

Healthcare providers can place orders for the Myriad MyRisk test online at


Below are additional frequently asked questions about the Myriad MyRisk test.

Who should consider a Myriad Genetics MyRisk genetic test?

Men may be a candidate for the Myriad Genetics MyRisk test if they:

  • have a personal history of any of the following: male breast cancer; metastatic prostate cancer; pancreatic, colon or rectal cancer
  • have a family history of any of the following: breast cancer under age 50; ovarian, metastatic prostate, pancreatic cancers; colon, rectal or uterine cancer under age 50

To help determine if genetic testing is appropriate, healthcare providers will refer patients to a genetic counselor who helps determine their risk of hereditary cancer and whether testing is right for them and their family.

What does the Myriad Genetics MyRisk genetic test measure?

The Myriad Genetics MyRisk genetic test uses a saliva sample to analyze 48 genes. The test identifies elevated risk for 11 hereditary cancers. Test results for MyRisk are presented in the following fashion:

  • Positive Result: A genetic mutation was found in one or more genes tested, putting the patient at increased risk for cancer.
  • Elevated Result: No genetic mutation was found, but the patient is at elevated risk of cancer based on family history, personal risk factors or additional genetic markers.
  • Negative Result: No genetic mutation was found in the genes tested. Risk for cancer depends on personal or family history.
  • Variant of uncertain significance: A change in a gene was identified, but it is not yet known if this change is associated with increased cancer risk.

Patients’ healthcare providers or genetic counselors will review the results with the patients, answer any questions and recommend next steps. See a sample Myriad Genetics MyRisk test report and learn more about interpreting this report.

Learn more 

Explore more information about the Myriad MyRisk test.


Hereditary Cancer Risk Assessment and Genetic Testing in the Community-Practice Setting

This study looked at the hereditary cancer risk assessment, education, and testing of patients in the community-based setting and found that genetic testing led to the identification of significant cancer risks that would not have been recognized without the multi-gene panel test.