Prostate cancer markers (PCMs) are molecules that can be found in blood, tissue, or body fluids that is a sign of a normal or abnormal process. You can learn about these markers by reviewing them based on the type of marker (blood, urine, tissue) or, through our PCMs bucket algorithm.

Below, individuals can select which test may be right for them based on our PCMs bucket algorithm (a printable copy of this algorithm can be found on our references and downloads page by clicking here). Simply click on the button in our PCMs bucket table that most represents the prostate cancer marker that may be suitable for your specific scenario. 

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Blood based Prostate Cancer Markers (PCMs)

There are a number of different blood based PCMs, including the Beckman Coulter's Prostate Health Index (phi), or the Opko 4K test. Each of these tests have shown to be superior to the prostate specific antigen (PSA) in identifying significant vs insignificant prostate cancer.  There is also ProstateNext, which is a blood or saliva genetic analysis. 

Urine based PCMs

In addition to blood tests, there are a few (currently available to be ordered by your doctor) tests available which test prostate cells present in the urine (after a digital rectal examination or DRE) which have shown to be very accurate in determining which individual may have high grade prostate cancer upon biopsy. 

Tissue based PCMs

For men who have had a prostate biopsy, there are several PCMs (currently available to be ordered by your doctor) which can help understand how aggressive the type of cancer is that was found on biopsy or after prostate surgery, or to indicate which areas of the prostate may be harboring prostate cancer if the biopsy was negative. These tests include The Prolaris Test by Myriad Genetics, the Decipher test by GenomeDx Biosciences, the Oncotype DX test by Genomic Health, and the ConfirmMDX test by MDxHealth. 

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