About the Ambry Score:
The Ambry Score is a genetic PCM that can be added on as a supplementary PCM to other tests, such as the ProstateNext test. The Ambry Score is known as a polygenic risk score (PRS), which means it can evaluate the genetic variants a man inherited at birth to determine that individual's risk of having developed or risk of eventually developing prostate cancer.
The Ambry Score evaluates an individual's risk by examining the patient's age at testing, their ethnicity, and 72 single nucleotide polymorphisms (SNPs). A SNP is an error that exists in one's genetic code, or DNA. These SNPs are unique to each individual, and are usually inherited from ones parents. Through researching populations of men, these 72 SNPs have been identified as being associated with prostate cancer risk. At the current time, the test is only available for men of Northern European descent.
The results of the Ambry Score, in combination with other tests, such as ProstateNext, can help your healthcare provider determine your risk of having developed or eventually developing prostate cancer as a result of these SNPs. These results, along with other personal risk factors and PCMs, can be used as a tool by your healthcare provider to develop a customized monitoring or treatment plan specific to your needs.
Below are several resources designed to help patients and their family better understand how the Ambry Score is used in a clinical setting, including a video as well as downloadable brochures.